4-Hydroxyisoleucine – Natural Amino Acid Extract for Blood Sugar Regulation
4-Hydroxyisoleucine is a non protein amino acid, isolated from Fenugreek seeds (Trigonella foenum-graecum). Fenugreek has a long history of use in the traditional Indian (Ayurveda) and Chinese medicines. It is a potential product as anti-diabetic, anti-dyslipidemic, muscle building, athletic diet and for skin and scalp health care applications.
🌿 4-Hydroxyisoleucine – Natural Amino Acid for Blood Sugar & Metabolic Health
4-Hydroxyisoleucine (4-HIL) is a non-proteinogenic amino acid found naturally in fenugreek (Trigonella foenum-graecum) seeds.
It has attracted growing interest due to its unique role in glucose metabolism and insulin sensitivity, making it one of the most studied bioactives for diabetes management, metabolic health, and weight control.
SGBio provides ≥98% pure 4-Hydroxyisoleucine, processed under GMP conditions with full analytical documentation. With local stock in New Zealand and global shipping, we support supplement manufacturers, research labs, and functional food innovators.
🔬 Key Bioactivities
Blood Sugar Regulation – Promotes healthy glucose uptake and helps balance blood sugar levels.
Insulin Sensitivity – Supports β-cell function and enhances insulin secretion.
Metabolic Balance – Improves lipid metabolism and energy homeostasis.
Antioxidant Properties – Reduces oxidative stress associated with metabolic disorders.
📦 Product Specifications
| Property | Details |
|---|---|
| Name | 4-Hydroxyisoleucine |
| Botanical Source | Trigonella foenum-graecum (Fenugreek seeds) |
| Molecular Formula | C₆H₁₃NO₃ |
| Molecular Weight | 147.17 g/mol |
| Appearance | White to off-white powder |
| Purity | ≥ 98% (HPLC) |
| Solubility | Soluble in water and alcohol |
| Shelf Life | 24 months (under proper storage) |
| Packaging | 1kg foil bags / 25kg fiber drums |
| Certification | CoA, MSDS, Third-party lab tested |
🧪 Application Areas
Blood Sugar & Insulin Support Formulas – dietary supplements for glucose control.
Nutraceuticals for Diabetes & Metabolic Syndrome – widely studied in type 2 diabetes.
Sports Nutrition – supports energy metabolism and recovery.
Functional Foods & Beverages – added to health drinks, protein powders, or fortified foods.
Research Use – metabolic health, obesity management, and bioactive compound studies.
🟩 Frequently Asked Questions
Q1: What is the source of 4-Hydroxyisoleucine?
A1: It is extracted from fenugreek seeds, a legume widely used in traditional medicine and functional foods.
Q2: How does it support blood sugar health?
A2: 4-HIL promotes insulin secretion and improves insulin sensitivity, helping regulate glucose metabolism.
Q3: What purity is available?
A3: SGBio offers ≥98% HPLC-tested purity, suitable for research and nutraceutical formulation.
Q4: Is it safe for human use?
A4: It is widely studied in nutraceuticals, but direct consumption must comply with local regulations and proper formulation.
Q5: Can I order small samples?
A5: Yes, samples are available for lab testing and pilot production.
⚠️ Regulatory Note
For research and industrial use only. Not intended for direct human consumption unless formulated according to local regulatory compliance.
📞 Supply & Support
SGBio provides high-purity 4-Hydroxyisoleucine with:
Full technical documentation (CoA, MSDS, third-party tests)
Flexible supply chain: from small samples to bulk orders
Local stock in New Zealand and export to global markets
📩 Contact us today for bulk pricing, samples, and regulatory support.



